50-27-1 MSDS - Estriol
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Estriol

Identification
Name Estriol
CAS Registry Number 50-27-1
Synonyms TRIDESTRIN;(16-alpha,17-beta)-estra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Estra-1,3,5(10)-triene-3,16,17-triol;(16-alpha,17-beta)-oestra-1,3,5(10)-triene-3,16,17-triol;(16alpha,17beta)-Oestra-1,3,5(10)-triene-3,16,17-triol;1,3,5-estratriene-3-beta,16-alpha,17-beta-triol;1,3,5-Estratriene-3beta,16-alpha,17-beta-triol;1,3,5-oestratriene-3-beta,16-alpha,17-beta-triol
Molecular Structure Estriol   50-27-1
Molecular Formula C18H24O3
Molecular Weight 288.38
mp: 280-282 ℃(lit.)
Hazard Codes: Details
Risk Statements: 60-61-40-45
Safety Statements: 53-22-36/37/39-45-36/37
Supplier
Lightchem Inc
Supply Precious metal catalyst
OLED Materials etc.
www.lightchem.com
 
Wiki & MSDS
50-27-1.pdf
Estriol
Estriol.svg
Estriol-3D-model.png
Clinical data
Pronunciation /ˌɛstrl/ ES-TRYE-ohl[citation needed]
Trade names Ovestin, others[1]
Routes of
administration
Oral, vaginal
ATC code
  • G03CA04 (WHO)
    G03CC06 (WHO)
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Biological half-life 5 hours[2]
Identifiers
Synonyms 16α-Hydroxyestradiol; Estra-1,3,5(10)-triene-3,16α,17β-triol
CAS Number
  • 50-27-1 YesY
PubChem CID
  • 5756
IUPHAR/BPS
  • 2821
DrugBank
  • DB04573 YesY
ChemSpider
  • 5553 YesY
UNII
  • FB33469R8E
KEGG
  • C05141 YesY
ChEBI
  • CHEBI:27974 YesY
ChEMBL
  • CHEMBL193482 YesY
ECHA InfoCard 100.000.021
Chemical and physical data
Formula C18H24O3
Molar mass 288.39 g·mol−1
3D model (JSmol)
  • Interactive image
  (verify)

Estriol (E3), also spelled oestriol, is a steroid, a weak estrogen, and a minor female sex hormone.[3][4] It is one of three major endogenous estrogens, the others being estradiol and estrone.[3] Levels of estriol in women who are not pregnant are almost undetectable.[5] However, during pregnancy, estriol is synthesized in very high quantities by the placenta and is the most produced estrogen in the body by far,[5][6] although circulating levels of estriol are similar to those of other estrogens due to a relatively high rate of metabolism and excretion.[6][7] Relative to estradiol, both estriol and estrone have far weaker activity as estrogens.[3] Although it is less commonly used than other estrogens, estriol is available for medical use throughout the world in a variety of formulations, including for oral and vaginal administration.[3]


 







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